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Itaconic acid

Name: Itaconic acid
Brand: TargetMol
SKU: T4837
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4837Cas No. 97-65-4

Alias methylene-butanedioicaci

Itaconic acid is a precursor for the synthesis of polymers, chemicals, and fuels, and has anti-inflammatory activity.Itaconic acid can be synthesized by fungi. It is also a macrophage-specific metabolite. It mediates crosstalk between macrophage metabolism and peritoneal tumors.

Itaconic acid

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Purity: 97.15%

Catalog No. T4837Alias methylene-butanedioicaciCas No. 97-65-4

Pack Size	Price	Availability
100 mg	$54	In Stock
500 mg	$105	In Stock
1 g	$147	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Batch Information

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Purity:97.15%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Itaconic acid is a precursor for the synthesis of polymers, chemicals, and fuels, and has anti-inflammatory activity.Itaconic acid can be synthesized by fungi. It is also a macrophage-specific metabolite. It mediates crosstalk between macrophage metabolism and peritoneal tumors.
Synonyms	methylene-butanedioicaci

Chemical Properties

Molecular Weight	130.1
Formula	C₅H₆O₄
Cas No.	97-65-4
Smiles	OC(=O)CC(=C)C(O)=O
Relative Density.	1.573 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (211.38 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.6864 mL	38.4320 mL	76.8640 mL	384.3198 mL
5 mM	1.5373 mL	7.6864 mL	15.3728 mL	76.8640 mL
10 mM	0.7686 mL	3.8432 mL	7.6864 mL	38.4320 mL
20 mM	0.3843 mL	1.9216 mL	3.8432 mL	19.2160 mL
50 mM	0.1537 mL	0.7686 mL	1.5373 mL	7.6864 mL
100 mM	0.0769 mL	0.3843 mL	0.7686 mL	3.8432 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc